The key issue is logistics, designing the set for a West End or Broadway production is heavily determined by that venue, plus sets would be built / ensembled specifically for and at that venue.
Put the show on tour, then your set and associated production has to be built / collapsible / transportable depending on the varying limitations on stage height (flying scenary in & out between acts as in a big production theatre, or having to compromise with static scenery as stage flexibility is limited), stage truck access, loading bay access, orchestra pit size (if any), stage size, stage angle, power availability, auditorium size and levels, audience view of the stage, ability to fly touring lights / PA or being forced to use the House system, plus whatever local 'Elf & Safety regulations you are limited by etc, etc, for whatever venues you're visiting.
The other factor which disappoints audiences are the performers, run a big production in The West End or Broadway and you'll get the stars, as most likely they live or can live locally. Put on a touring production and most named performers won't do it, so the audience enthusiasm for the show is diminished some what.
So any touring production of an award winning West End / Broadway show will be different to the original show.