babybear2 Posted April 26 Posted April 26 5 hours ago, floridarob said: You wouldn't believe how many times the local clients are direct, so fucking direct....no mincing words. I let them know to "close the deal"...now power, no money....some I tease that if they can't get hard, they'll be the bottom....... If guys know that they have performance issues, they'll already have their remedio, to take care of that deficiency ..... DON'T accept subpar performance.....that is all 😉 what you said about local clients, makes total sense to me. I often observe local clients spend 30+ minutes chatting and teasing with garatos before sealing a deal, and I suspect they also pay less than gringos, maybe 100R only well, it is their country, they speak portuguese, and they go a few times every week, they deserve better Mavica 1 Quote
Canadianbtmguy Posted April 26 Author Posted April 26 On 4/19/2024 at 10:02 AM, Riobard said: AFAIK Descovy, in contrast to Truvada, is not indicated anywhere for on-demand / event-driven 2-1-1 HIV PrEP either formally or off-label, as corroborated by NYC Health, IAS, CATIE, etc. .... If the guy were to eventually seek PrEP formally he might reveal that a visiting gringo had provided a controlled prescription-dependent drug not ANVISA-approved in Brazil and with an incorrect dosing regimen instruction to boot. I wanted to acknowledge the accuracy of the first paragraph that while both Truvada and Descovy, are approved for PrEP generally, only Truvada is approved for on-demand/2-1-1, and I did not know that. That being said, my PrEP prescriber said it was not approved "yet" and he did not see any reason why this very similar medication would not be eventually approved; he said that if someone was going to have sex and did not have Truvada it would not be an inappropriate choice. (Grated the GP and my situation was not exactly that: the doctor's example was that someone was going to have sex regardless; ours was that he would provided that he had PrEP) As to the third paragraph, I'm not really sure of the harm of such a revelation. To him: is there any doubt that patients regularly reveal taking drugs that are not only not-ANVISA-approval but illegal? To me: dispensing non-ANVISA approved medications without a pharmacy license? 🤣 Quote
Members Riobard Posted April 27 Members Posted April 27 3 hours ago, Canadianbtmguy said: I wanted to acknowledge the accuracy of the first paragraph that while both Truvada and Descovy, are approved for PrEP generally, only Truvada is approved for on-demand/2-1-1, and I did not know that. That being said, my PrEP prescriber said it was not approved "yet" and he did not see any reason why this very similar medication would not be eventually approved; he said that if someone was going to have sex and did not have Truvada it would not be an inappropriate choice. (Grated the GP and my situation was not exactly that: the doctor's example was that someone was going to have sex regardless; ours was that he would provided that he had PrEP) As to the third paragraph, I'm not really sure of the harm of such a revelation. To him: is there any doubt that patients regularly reveal taking drugs that are not only not-ANVISA-approval but illegal? To me: dispensing non-ANVISA approved medications without a pharmacy license? 🤣 Your intentions were good but I was just wondering what the impact on the fellow would be in terms of his views about you if a local clinician were to later reflect that the drug and dosage of his initiation was incorrect. In actuality, he might be more inclined to seek PrEP at this point and that is not a bad thing. He might not know enough to realize the medication disconnect if and when Truvada is dispensed. Anyway, as you indicate, now you know. It’s certainly not egregious to sub one for the other in a pinch according to the idea that having some prophylaxis is better than none. However, the prospects for eventual on-demand Descovy appear slim. There is no registered trial assessing its non-inferiority to event-driven Truvada. There is minimal interest in additional innovative on-demand regimens and the strategy of trading off specific drug toxicities in reduced uptake may be less paramount. One proposed study has not achieved lift-off. Even if it gets off the ground the endpoint is about 2028. It is no longer feasible ethically to have placebo-control arms, so how to approximate a gold standard method is more complex. Although the Descovy comparator is Truvada, the control group idea is substituted with background HIV incidence in non-recruited MSM. That itself reduces the analytical rigour. Moreover, the methodology described is the usual Truvada 2-1-1 but Descovy 1-1 (reduced lead-in dose loading as well as absent the final post-intercourse ‘for good measure’ dose), counterintuitive relative to the logical assumption of equal number of tablets one would expect in study arms. Demonstrating daily Descovy for vaginal intercourse PrEP efficacy is probably of greater importance. Canadianbtmguy and Xclay 2 Quote
Canadianbtmguy Posted June 11 Author Posted June 11 I just spent a long weekend in SP (during which I never even made it to Lagoa) so if anyone would like my recommendation on SP garotocomlocal tops who bbk just let me know. With over 1000 listings in SP it’s a pretty time consuming process (compared to some other escort sites garotocomlocal makes it unusually time consuming as it doesn’t even have the guys fill in their basic stats) I’m looking for tall guys (min 1.80) so I end up contacting a lot of guys that if only it had these sort of fill in fields. In many ways, it seems surprising the low percentage of guys who even respond to the initial contact (long before any talk of condoms) I have a Brazilian number and a friendly WhatsApp pic, yet I would say less than 20% reply to the initial inquiry (a bit more among the “destaque” ads that pay a lot for the higher-up position): “Olá, boa noite. Tudo bem? Estou no SP, vi seu anúncio e me interessei. Por favor, deixe-me saber se Vc está disponível hoje/amanhã, bem como seu caché. obrigado!” incidentally if anyone has some good recommendations for Rio i have far fewer (as does garotoscomlocal with only 400something compared to SP 1000+) and would really welcome some recommendations. when I was here in the other seasons, I would stay in Rio only Monday through Wednesday and then escape to the not as hot temperatures and lower humidity of SP. But now I have the next 10 days here in Rio. (A bit unluckily,unseasonable temperatures as high as summer around 30 every day are predicted throughout the period, although it is true, the humidity is less) I should mention that Really the best guy That I have met in the last year in terms of pure sex, I was lucky to meet him a couple of times in Rio before he rather predictably ran off to Europe (London), where, as of a few days ago he remains, but if anyone finds themself looking for an amazing Brazilian top in London (no doubt at more than the 350 reais I was lucky to get him at) lmk Mavica and babybear2 1 1 Quote
Members Latbear4blk Posted June 12 Members Posted June 12 2 hours ago, Canadianbtmguy said: I just spent a long weekend in SP (during which I never even made it to Lagoa) so if anyone would like my recommendation on SP garotocomlocal tops who bbk just let me know. With over 1000 listings in SP it’s a pretty time consuming process (compared to some other escort sites garotocomlocal makes it unusually time consuming as it doesn’t even have the guys fill in their basic stats) I’m looking for tall guys (min 1.80) so I end up contacting a lot of guys that if only it had these sort of fill in fields. In many ways, it seems surprising the low percentage of guys who even respond to the initial contact (long before any talk of condoms) I have a Brazilian number and a friendly WhatsApp pic, yet I would say less than 20% reply to the initial inquiry (a bit more among the “destaque” ads that pay a lot for the higher-up position): “Olá, boa noite. Tudo bem? Estou no SP, vi seu anúncio e me interessei. Por favor, deixe-me saber se Vc está disponível hoje/amanhã, bem como seu caché. obrigado!” incidentally if anyone has some good recommendations for Rio i have far fewer (as does garotoscomlocal with only 400something compared to SP 1000+) and would really welcome some recommendations. when I was here in the other seasons, I would stay in Rio only Monday through Wednesday and then escape to the not as hot temperatures and lower humidity of SP. But now I have the next 10 days here in Rio. (A bit unluckily,unseasonable temperatures as high as summer around 30 every day are predicted throughout the period, although it is true, the humidity is less) I should mention that Really the best guy That I have met in the last year in terms of pure sex, I was lucky to meet him a couple of times in Rio before he rather predictably ran off to Europe (London), where, as of a few days ago he remains, but if anyone finds themself looking for an amazing Brazilian top in London (no doubt at more than the 350 reais I was lucky to get him at) lmk Do you check the dates when the profiles were opened in garotocom? I am not 100% sure, but I think the site does not archive the ads after the garotos stop paying and checking them. You may have a higher rate of response on featured ads because those are current, active, paying GPs. KeepItReal, Mavica and Julian9999 3 Quote
Canadianbtmguy Posted June 13 Author Posted June 13 On 6/11/2024 at 5:40 PM, Latbear4blk said: Do you check the dates when the profiles were opened in garotocom? I am not 100% sure, but I think the site does not archive the ads after the garotos stop paying and checking them. You may have a higher rate of response on featured ads because those are current, active, paying GPs. Very good point. In fact, one guy did write back and say that he is no longer working as a boy. I probably won't stop looking at the small ones because my favorite guy in SP is there. And I do like the idea of hiring guys for whom it is not their life, they are just doing it a little on the side. Speaking of just doing it a little on the side, yesterday was Brazilian valentines day and I met a guy (sauna not online) who had stopped in because he wanted to take his wife out to dinner but he stopped in after work because he needed to make the money first. Talk about waiting til the last minute Back to garotocomlocal ads, I noticed today that SP has hit 1100 whereas Rio had fallen below 400. With SP's population not even double Rio's, a surprising ratio. Quote