t0oL1 Posted November 12, 2022 Posted November 12, 2022 https://www.vice.com/en/article/aeqj38/botox-could-be-the-new-penis-wonder- For a man who wishes he was more of a "shower," there aren't a whole lot of options on the market, short of expensive and risky surgical procedures and stretching devicesthat need to be worn several hours per day for months on end. Botox, however, could change that. In a 2009 study, researchers used Botox to try and help guys who had a "hyperactive retraction reflex." In other words, these were men who experienced a lot more "shrinkage" (in the words of George Costanza) than others. Doctors made four injections around the base of the penis, with the goal of paralyzing the muscles responsible for the shrinkage reflex, known as the tunica dartos. And it worked. It could help treat erectile dysfunction, too. A new paper published in The Journal of Sexual Medicine argues that Botox could be a "game changer" when it comes to treating erectile dysfunction (ED). The thought here is that Botox could be used to paralyze the smooth muscles inside the erectile chambers of the penis. By relaxing these muscles, blood should be able to flow into the penis more easily. A small study conducted in Egypt that was reported last year provided some initial support for this idea: Men with ED who received a Botox injection demonstrated improvements in penile blood flow. One patient, however, experienced priapism afterward—a prolonged erection that wouldn't go away on its own. This tells us that dosage is going to be very important: Too much muscle relaxation isn't a good thing. unicorn 1 Quote
Mavica Posted November 13, 2022 Posted November 13, 2022 2 hours ago, t0oL1 said: One patient, however, experienced priapism afterward—a prolonged erection that wouldn't go away on its own. Unrelated, but some similarities: 25 years ago a friend of mine underwent penile implant surgery. A pumped-up penis balloon of sorts. A pump control was placed behind his ball sac. He said the surgery was painful. He hadn't fucked his partner in more than a decade. The first time he tried the pump he was rock-hard and the two of them had wonderful sex. The pump relief valve malfunctioned and his long dick stayed hard; wouldn't deflate. His surgeon was out of town for a couple of weeks and the office told him to strap the big dick to his thigh with an "Ace" bandage. I told him to head to the nearest gay bath house and fuck everyone he could. Why waste such a gift. He didn't. When the surgeon returned he had the implant removed. No more sex for him (he would only top, no bottoming). $4,000 and his desires unfulfilled/wasted. Be careful what we wish for. Quote
Olddaddy Posted November 13, 2022 Posted November 13, 2022 I had the P shots last year , didn't really do much , $2500 for 2 shots Cheaper in Bangkok though Quote
maump Posted November 13, 2022 Posted November 13, 2022 5 hours ago, Olddaddy said: I had the P shots last year , didn't really do much , $2500 for 2 shots Cheaper in Bangkok though what is the p shots? botox? Quote
Members Riobard Posted November 13, 2022 Members Posted November 13, 2022 Old article. Currently Botox use still lacks robust clinical data for urological application whether it be retraction, premature ejaculation, erectile dysfunction, or other urogenital concerns. After all that time a mere single flimsy meta-analysis of [and minimally measurement-overlapping] RCTs … recommending further research, yet no appreciable evidence of trials underway moving the agenda along. Not necessarily bunk but a long way from farm to table. No prospective shift from off-label to more standardized authorized regulated use any time soon. PDE5 inhibitor stakeholders need not worry about stiff competition from Botox. Quote
Members Riobard Posted November 13, 2022 Members Posted November 13, 2022 2 hours ago, maump said: what is the p shots? botox? PRP: platelet rich plasma; more recent. Not to be confused with long-standing product TripleP injection; prostaglandin/ papaverine/ phentolamine. PRP: lacks robust gold standard clinical data. At this point I’d say it’s bunk-ish and money-grab-ish. There may be ongoing enroll-able research for its application viz Peyronie’s Disease or Erectile Dysfunction. Quote
maump Posted November 13, 2022 Posted November 13, 2022 1 hour ago, Riobard said: PRP: platelet rich plasma; more recent. Not to be confused with long-standing product TripleP injection; prostaglandin/ papaverine/ phentolamine. PRP: lacks robust gold standard clinical data. At this point I’d say it’s bunk-ish and money-grab-ish. There may be ongoing enroll-able research for its application viz Peyronie’s Disease or Erectile Dysfunction. ah yes, I had heard of it as He-shot. seemed like snake oil. the "idea" of botox relaxing the muscles to allow more blood flow into the penis made some sense. An erection begins with sensory and mental stimulation. During sexual arousal, nerve messages begin to stimulate the penis. Impulses from the brain and local nerves cause the muscles of the corpora cavernosa to relax, allowing blood to flow in and fill the open spaces. The blood creates pressure in the corpora cavernosa, making the penis expand and creating an erection. The tunica albuginea (the membrane surrounding the corpora cavernosa), helps to trap the blood in the corpora cavernosa, sustaining the erection. Erection is reversed when muscles in the penis contract, stopping the inflow of blood and opening outflow channels. Quote
maump Posted November 13, 2022 Posted November 13, 2022 Penis girth enhancement with injection is shown to be effective for a couple of years. it increases the "show" when soft and thickness when hard. one of my favorite hung asian american porno "tops" got it. he loved it. didn.t need it, but was happy. RaY DEXTER TWITTER @RayDexterXXX https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987147/ Quote
Members Riobard Posted November 13, 2022 Members Posted November 13, 2022 In case there’s confusion PPP for the tripartite intracavernosal injection (ICI) mode I referenced above is now easily conflated with the control group term for PRP research: platelet poor plasma (PPP), while my representation of ICI tripleP or ICI PPP is now typically represented as ICI Trimix which may be employed as the on-demand comparator control in Botox research, where Botox is, in contrast to Trimix, extended depot model. Anywhoooo, these trials are basically on life support. Fillers for girth enhancement were introduced here and have nothing to do with the topic of Botox or Platelet Rich Plasma. Botox would be utilized for ED that is refractory to PDE5Is or for whom PFE5I reactogenicity contraindicates its indication. The risk of Botox toxicity would render it a poor candidate for cosmetic (ie, size) use. Any true difference yield would be lost on the 3 blind mice used in animal research because they wouldn’t have a sense of the optics of their dick girth change via muscle tone alteration. Quote
Members Lucky Posted November 14, 2022 Members Posted November 14, 2022 Gosh. My cock got bigger just reading this thread! numerito and kokopelli3 1 1 Quote
reader Posted November 18, 2022 Posted November 18, 2022 It’s no wonder there are so many advertisements for drugs in media. When industry knows it can make men believe that they’re girth deficient, sky’s the limit. TMax 1 Quote